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Analysis of sunitinib malate (APK #651)

Sunitinib malate is a small molecule used as a kinase inhibitor in the targeted cancer therapy for treatment of renal cell carcinoma (RCC), gastrointestinal stromal tumors (GIST) and pancreatic neuroendocrine tumors (pNET). Development of robust and sensitive chromatographic method for quantification of sunitinib at low concentration in different matrices such as serum, plasma, urine is highly demanded.